Sensitive Skin Serum Picks
Sofia Alvarez
| 18-08-2026
· Fashion team
Hello Friends! Sensitive skin can make serum shopping feel like a guessing game. I usually look for formulas that have a clear purpose without turning my routine into a long list of strong actives.
Hydration, barrier support, and a gentle approach matter more to me than chasing the most complicated ingredient list.

1. medicube PDRN Pink Peptide Serum with Salmon DNA

The medicube PDRN Pink Peptide Serum has a more treatment-oriented feel, but the appeal for me comes from its combination of PDRN and peptides. PDRN has become popular in Korean skincare, particularly in formulas designed around skin-conditioning and a healthier-looking complexion. I would reach for a serum like this when my skin looks tired and I want something that feels more restorative than aggressively active.

2. Cetaphil Ceramide Serum Skin Barrier Repair Sensitive Skin

Cetaphil is the name I naturally associate with uncomplicated skincare, so a ceramide-focused serum makes sense for sensitive skin routines. Ceramides are important components of the skin barrier, and including them in a serum can be useful when the complexion feels dry, tight, or easily irritated. I would personally keep this one in mind during periods when my skin seems to be asking for comfort rather than more active ingredients. It fits nicely underneath moisturizer and does not require a complicated routine around it.

3. PURITO TXA 6% Niacinamide Serum for Sensitive Skin

PURITO TXA 6% Niacinamide Serum takes a different direction with tranexamic acid (TXA) and niacinamide. I find this combination interesting when uneven-looking tone and discoloration are bigger concerns. Sensitive skin does not necessarily mean avoiding every active ingredient. It means introducing ingredients thoughtfully and paying attention to how the skin reacts. I would start slowly rather than applying it aggressively every day from the beginning.
I would choose according to what my skin needs at the moment. Cetaphil makes the most sense when barrier support is the priority, medicube appeals to me for a more replenishing peptide-focused routine, while PURITO fits better when improving the appearance of uneven tone is the goal. For sensitive skin, I think consistency wins over complexity. A serum that feels comfortable enough to use regularly will always have a better place in my routine than an exciting formula that leaves my skin unhappy.